Autoimmune Community London Let's Get Better Together! (5).png

Leaky gut
(Intestinal Permeability)

Leaky gut, also known as increased intestinal permeability, is a condition where the lining of the intestine becomes more permeable than normal.

In a healthy gut, the intestinal lining acts as a barrier, allowing nutrients to be absorbed while preventing harmful substances from entering the bloodstream. However, in leaky gut, the tight junctions between the cells of the intestinal lining become loose, allowing undigested food particles, toxins, and bacteria to leak into the bloodstream.

This can trigger an immune response and lead to inflammation throughout the body, contributing to various health issues. Leaky gut has been associated with autoimmune diseases, digestive disorders, food sensitivities, allergies, skin conditions, and even mental health disorders.

Factors that can contribute to leaky gut include a poor diet, chronic stress, medications, infections, imbalances in the gut microbiome, and genetic predisposition.

Addressing leaky gut involves identifying and addressing the underlying causes, such as improving gut health, reducing inflammation, and supporting the healing of the intestinal lining.

CAN YOU TEST FOR LEAKY GUT?

Testing for leaky gut can be challenging, as there is no single definitive test available. However, healthcare practitioners may use various methods to assess gut permeability and identify potential signs of leaky gut. Some common approaches include:

Intestinal Permeability Test with Cyrex Laboratories: This test can provide inevidence of increased gut permeability and inflammation by measuring intestinal permeability to large molecules, which inflame
the immune system.

Stool Tests: Comprehensive stool tests may assess gut health, including the presence of pathogens, beneficial and harmful bacteria, and markers of gut inflammation.

It's important to note that these tests are not definitive and may have limitations.

The interpretation of results should be done in conjunction with a healthcare professional experienced in gut health and functional medicine.

Additionally, symptoms, medical history, and clinical evaluation are important factors in diagnosing and managing leaky gut. A healthcare practitioner will consider all relevant information to guide treatment and support gut healing.

Leaky gut can manifest with a variety of symptoms, and it can vary from person to person. Some common symptoms associated with leaky gut include::

Digestive Issues: These may include bloating, gas, abdominal pain, diarrhea, constipation, or irritable bowel syndrome (IBS)-like symptoms.
Food Sensitivities: Leaky gut can contribute to the development of food sensitivities or allergies, leading to adverse reactions after consuming certain foods.
Fatigue and Low Energy: Chronic fatigue, low energy levels, and a general feeling of tiredness can be signs of leaky gut.
Joint Pain and Inflammation: Leaky gut can trigger an inflammatory response in the body, resulting in joint pain, stiffness, and inflammation.
Skin Problems: Skin conditions such as acne, eczema, psoriasis, or rashes may be linked to leaky gut due to the systemic inflammation it can cause.
Brain Fog and Cognitive Issues: Some individuals with leaky gut may experience difficulty concentrating, memory problems, and overall cognitive dysfunction.
Mood Disorders: Leaky gut can impact mental health and contribute to symptoms such as anxiety, depression, mood swings, and irritability.
Autoimmune Conditions: There is evidence to suggest that leaky gut plays a role in the development or exacerbation of autoimmune diseases, such as rheumatoid arthritis, lupus, or celiac disease.

What Causes leaky gut?

Leaky gut, also known as increased intestinal permeability, can have various underlying factors contributing to its development.

Some of the common factors associated with leaky gut include:

Imbalance of Gut Microbiota: Disruption in the balance of beneficial and harmful bacteria in the gut can lead to inflammation and compromise the integrity of the gut lining.

Chronic Inflammation: Systemic inflammation, whether caused by dietary factors, chronic infections, or other health conditions, can contribute to the breakdown of the gut barrier.

Poor Diet: Consuming a diet high in processed foods, refined sugars, artificial additives, and inflammatory fats can contribute to gut inflammation and damage.

Food Sensitivities and Allergies: Certain foods, such as gluten, dairy, and other common allergens, may trigger immune reactions and inflammation in the gut.

Chronic Stress: Prolonged stress can disrupt the gut-brain axis and affect gut health. Stress hormones and neurotransmitters can impact gut function and increase intestinal permeability.

Medications: Long-term use of non-steroidal anti-inflammatory drugs (NSAIDs), antibiotics, proton pump inhibitors (PPIs), and other medications can disrupt the gut microbiota and contribute to leaky gut.

Environmental Toxins: Exposure to environmental toxins, such as heavy metals, pesticides, and pollutants, can impair gut barrier function and contribute to inflammation.

Genetic Predisposition: Some individuals may have genetic variations that make them more susceptible to developing leaky gut.

It's important to note that leaky gut is a complex condition, and multiple factors can contribute to its development.

Identifying and addressing these underlying factors, along with implementing a comprehensive treatment approach, is essential for healing and restoring gut health.

Leaky Gut and Nutritional Supplements

While it's important to consult with a qualified healthcare professional before starting any new supplements, here are some supplements that are commonly used to support gut health and may be helpful for individuals with leaky gut:

Short-chain fatty acids (SCFAs): SCFAs,, particularly butyrate, can strengthen the gut barrier, reduce inflammation, and modulate the immune response in the gut. They promote the production of tight junction proteins, maintain gut integrity, and prevent the leakage of harmful substances. SCFAs also possess anti-inflammatory properties and help balance the immune reaction to prevent excessive inflammation and immune activation.

Deglycyrrhizinated Licorice (DGL): DGL is known for its potential to support the health of the gastrointestinal lining. It may help to promote the growth and repair of the gut lining, potentially reducing permeability and supporting the integrity of the intestinal barrier. DGL also has natural anti-inflammatory and soothing properties. It may help to calm inflammation in the gut, which can contribute to leaky gut symptoms.

L-Glutamine: Glutamine is an amino acid that plays a vital role in gut health and integrity. It can support the healing of the intestinal lining and reduce inflammation.

Quercetin: Quercetin is a flavonoid with anti-inflammatory properties that can help reduce gut inflammation and improve gut barrier function.

Betaine HCl and Digestive Enzymes: Digestive support can assist in the breakdown and absorption of nutrients, easing the burden on the digestive system and potentially reducing gut inflammation.

Zinc: Zinc is an essential mineral that supports gut health and helps maintain the integrity of the intestinal lining. It also plays a role in immune function.

Omega-3 Fatty Acids: Omega-3 fatty acids, found in fish oil or algae-based supplements, have anti-inflammatory properties and may help reduce gut inflammation.

Probiotics: Probiotics are beneficial bacteria that can help restore the balance of gut microbiota and support gut health. Look for strains such as Lactobacillus and Bifidobacterium.

Aloe Vera: Aloe vera gel or supplements may have soothing effects on the gut lining and support gut healing.

It's important to note that the effectiveness of these supplements can vary depending on individual needs and underlying factors. Working with a healthcare professional experienced in gut health can help determine the most appropriate supplements and dosages for your specific situation.

WHAT ABOUT THE DIET?

Diet plays a crucial role in managing leaky gut and promoting gut health.

Here are some dietary considerations:

Remove Trigger Foods: Identify and eliminate foods that may contribute to gut inflammation and worsen symptoms. Common trigger foods include processed foods, refined sugars, gluten, dairy, and certain food additives.

Focus on Whole Foods: Emphasize a whole foods-based diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats. These foods provide essential nutrients and support gut health.

Increase Fiber Intake: Include plenty of fiber in your diet from sources like fruits, vegetables, legumes, and whole grains. Fiber promotes healthy digestion, feeds beneficial gut bacteria, and helps maintain a healthy gut barrier.

Probiotics and Fermented Foods: Consume probiotic-rich foods such as yogurt, sauerkraut, kimchi, and kefir. These foods introduce beneficial bacteria into the gut and support a healthy microbiome.

Omega-3 Fatty Acids: Include foods rich in omega-3 fatty acids, such as fatty fish (salmon, mackerel), flaxseeds, chia seeds, and walnuts. Omega-3s have anti-inflammatory properties and can help reduce gut inflammation.

Stay Hydrated: Drink plenty of water throughout the day to support optimal digestion and maintain adequate hydration.

Minimize Alcohol and Caffeine: Limit or avoid alcohol and caffeine, as they can irritate the gut and contribute to inflammation.

If you're feeling overwhelmed and unsure of where to start in addressing your gut symptoms, don't hesitate to reach out to us.

Our team is here to help you navigate through the confusion and develop a personalised treatment plan tailored to your specific needs.

We have experience in uncovering the root causes of gut issues and can guide you towards optimal gut health. Contact us today to begin your journey towards better digestive well-being.

"Heal the gut, heal the body.

Restoring gut health is the key to overall well-being."

Leaky gut (Intestinal Permeability)

Leaky Gut and Nutritional Supplements

Leaky gut
(Intestinal Permeability)